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Trials

Use of TREM-1 Protein to Differentiate Viral and Bacterial Pneumonias in Intubated Children

8 Aug 2008
The purpose of this study is to determine whether a protein called TREM-1 can be used to differentiate viral and bacterial pneumonias in children who are on ventilator support. We propose that the ... › More

Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission

22 Jul 2008
The purposes of this study are to determine whether Carraguard® Gel can prevent the transmission of HIV when used during vaginal intercourse, and to confirm that the ... › More

Evaluation Of Valaciclovir In Patients With Chickenpox

18 Jul 2008
This study will assess the safety and efficacy, and the pharmacokinetics of aciclovir and valaciclovir in children with chickenpox following oral administration of ... › More

Evaluation of a Combined Vaccine Against 4 Viral Childhood Diseases: Measles, Mumps, Rubella and Chickenpox.

1 Jul 2008
A study to evaluate GlaxoSmithKline Biologicals’ live attenuated varicella vaccine and GlaxoSmithKline Biologicals’ combined measles-mumps-rubella-varicella vaccine in the prevention of ... › More

Treatment of Deficient Subclass or Anti-Polysaccharide Antibody

25 Apr 2008
There is no consensus on the treatment of patients with recurrent infections and isolated immunoglobulin G (IgG)-subclass deficiency and/or selective antipolysaccharide antibody deficiency. ... › More

Treatment of Deficient Subclass or Anti-Polysaccharide Antibody Response (Subklasse)

14 Apr 2008
There is no consensus on the treatment of patients with recurrent infections and isolated immunoglobulin G (IgG)-subclass deficiency and/or selective antipolysaccharide antibody deficiency. ... › More

Truvada Versus Truvada Plus HBIG in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplant

23 Feb 2008
The objective of this study is to evaluate the safety and antiviral efficacy of the combination therapy (emtricitabine/tenofovir disoproxil fumarate), plus or minus Hepatitis B Immunoglobulin (HBIG) ... › More

Treatment of Children With Obstructive Sleep Apnoea and Laryngomalacia: The Role of Laser Supraglottoplasty

7 Dec 2007
This is a research study of the effect of treating laryngomalacia (floppiness of tissue on top of the voice box that can possibly block breathing) found in association with obstructive sleep apnoea ... › More

ASP2151 in Subjects With Recurrent Episodes of Genital Herpes

1 Dec 2007
A study of ASP2151 in subjects with recurrent outbreaks of genital herpes. › More

Isavuconazole in the Treatment of Candidemia and Other Invasive Candida Infections

3 Sep 2007
The purpose of the study is to compare the safety and efficacy of Isavuconazole versus caspofungin followed by voriconazole in the treatment of candidemia and other invasive Candida infections. › More

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Research

PulmonarOM (Bacterial Lysates) in Respiratory Tract Infections

12 Jul 2008
Primary aim:To evaluate the efficacy of Pulmonarom in the decrease of interleukin-4/interferon gamma after second period of treatment.Secondary ... › More

Safety and Immunogenicity of 2 Formulations of an Intramuscular A/H5N1 Pandemic Influenza Vaccine in Children

30 May 2008
This is an open, randomised, multicentre clinical trial.Objectives:To describe the safety profiles during the 21 days following each primary and booster ... › More

Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission

10 Mar 2008
The purposes of this study are to determine whether Carraguard® Gel can prevent the transmission of HIV when used during vaginal intercourse, and to confirm that the gel is safe for vaginal use. › More

Evaluation Of Valaciclovir In Patients With Chickenpox

24 Nov 2007
This study will assess the safety and efficacy, and the pharmacokinetics of aciclovir and valaciclovir in children with chickenpox following oral administration of valaciclovir, for the purpose of ... › More

Intravenous Pertussis Immune Globulin in Patients With Severe Childhood Pertussis Infection

16 Sep 2007
Objective:Assess the efficacy of a single infusion of a high titer pertussis immune globulin for the treatment of severe pertussis in children. › More

Study Evaluating the Safety, Immunogenicity and Tolerability of Meningococcal Group B Vaccine in Healthy Adults

10 Aug 2007
To determine the safety & immunogenicity of a potential vaccine against meningococcal B disease › More

A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea

9 Aug 2007
This study aims to determine if an investigational drug is safe and effective for treating symptoms of C. difficile-associated diarrhea (CDAD) and lowering the risk of repeat episodes of CDAD. The ... › More

Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old

23 Jul 2007
Main goal of this study is to compare the occurrence of serious adverse events (SAEs) between the herpes simplex (gD2-AS04) vaccine group and the Saline control group throughout the study period (up ... › More

Truvada Versus Truvada Plus HBIG in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplant

1 Jul 2007
The objective of this study is to evaluate the safety and antiviral efficacy of the combination therapy (emtricitabine/tenofovir ... › More

Study to Evaluate the Efficacy of the Human Papillomavirus Vaccine in Healthy Adult Women of 26 Years of Age and Older.

26 Jun 2007
This study will evaluate the immune responses, safety and efficacy of the investigational HPV vaccine in women who are 26 years of age or older. Infection with human papilloma virus (HPV) has been ... › More

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